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American Society of Microbiology ABMM Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Laboratory Management and Safety | 15-20% | - Regulatory compliance (CLIA, OSHA) - Laboratory safety and biosafety - Personnel management - Quality assurance and control |
| Clinical Mycology | 10-15% | - Fungal identification - Opportunistic and endemic mycoses - Antifungal susceptibility |
| Clinical Virology | 10-15% | - Viral identification methods - Viral culture techniques - Molecular and serological assays |
| Clinical Bacteriology | 30-35% | - Molecular detection methods - Emerging and fastidious bacterial pathogens - Antimicrobial susceptibility testing - Bacterial identification and characterization |
| Clinical Parasitology | 10-15% | - Molecular diagnostics - Life cycles and transmission - Parasite identification |
| Diagnostic Microbiology Applications | 15-20% | - Specimen collection and processing - Consultation with clinicians - Emerging technologies and automation - Interpretation of results |
American Society of Microbiology ABMM Sample Questions:
1. A patient develops a febrile illness with a diffuse petechial rash after a camping trip. Serological testing reveals a four-fold rise in antibody titer to Rickettsia rickettsii. The vector responsible for transmitting this organism is a:
A) Louse
B) Flea
C) Mosquito
D) Tick
2. A patient with a history of chronic lung disease develops a severe pneumonia. Bronchoalveolar lavage fluid reveals the presence of numerous cysts containing multiple nuclei, which stain positively with silver stains but poorly with Gram stain. The patient's CD4+ T-cell count is within the normal range. The MOST likely causative organism and the preferred treatment are:
A) Blastomyces dermatitidis; itraconazole.
B) Pneumocystis jirovecii; trimethoprim-sulfamethoxazole.
C) Histoplasma capsulatum; amphotericin B followed by itraconazole.
D) Paragonimus westermani; praziquantel.
3. A clinical microbiology laboratory is preparing a Gram stain of a mixed bacterial culture containing both Gram-positive and Gram-negative organisms. The correct order of reagents used in the Gram staining procedure is:
A) Safranin, crystal violet, decolorizer, iodine
B) Decolorizer, crystal violet, iodine, safranin
C) Iodine, crystal violet, decolorizer, safranin
D) Crystal violet, iodine, decolorizer, safranin
4. A traveler returning from a tropical region presents with fever, chills, and jaundice. Peripheral blood smear reveals the presence of ring-shaped parasites within erythrocytes. Further laboratory testing shows a positive result for Plasmodium falciparum histidine-rich protein 2 (HRP2). The MOST appropriate treatment for this patient is:
A) Amphotericin B
B) Metronidazole
C) Primaquine and a blood schizonticide (e.g., artemisinin-based combination therapy)
D) Mebendazole
5. A patient with a history of recurrent sinopulmonary infections and bronchiectasis is diagnosed with primary ciliary dyskinesia. Sputum cultures are most likely to persistently grow which of the following organisms?
A) Pseudomonas aeruginosa
B) Streptococcus pneumoniae
C) Haemophilus influenzae
D) Moraxella catarrhalis
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: B | Question # 3 Answer: D | Question # 4 Answer: C | Question # 5 Answer: C |





